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Sample Questions

The following are examples of question types that examinees may encounter when taking the NAPLEX. These questions are presented as examples to familiarize examinees with their formats and are not intended to represent content areas on the NAPLEX. Every examinee is presented with the opportunity to take a tutorial at the testing center prior to initiating the NAPLEX. The tutorial instructs examinees on how to respond to all of the types of questions that could be presented on the examination. NABP strongly encourages each examinee to take the tutorial in order to become familiar with how to submit responses in the computer-based examination.

Which of the following vaccines is contraindicated in immunocompromised patients?

  • A. Pneumococcal polysaccharide
  • B. Varicella
  • C. Meningococcal conjugate
  • D. Subcutaneous influenza

What counseling information should a pharmacist provide to a patient taking oral tacrolimus?

  • C. If a dose is missed, double up on the next dose
  • D. Do not drink alcohol while taking this medication
  • B. Avoid grapefruit and grapefruit juice
  • E. Medication levels need to be monitored
  • A. Avoid live virus vaccinations

Reference: https://nabp.pharmacy/programs/examinations/naplex/

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Below is the North American Pharmacist Licensure Examination Format

  • Passing score: Scaled 75
  • Number of questions: 250
  • Format: Multiple choices, multiple answers
  • Length of Examination: 6 hours
  • Language: English

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NABP NAPLEX Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Foundational Knowledge for Pharmacy Practice25%- Pharmaceutical Science Principles
  • 1. Pharmacology
    • 2. Pharmacokinetics, Pharmacodynamics, Pharmacogenomics
      • 3. Pharmaceutics
        - Pharmaceutical Calculations
        • 1. Dosage & Administration Calculations
          • 2. Patient Parameters & Lab Measures
            • 3. Dose Conversions
              - Pharmaceutical Compounding
              • 1. Nonsterile Preparations
                • 2. Sterile Preparations
                  Topic 2: Pharmacy Management & Leadership5%- Inventory & Supply Chain
                  - Quality Improvement & Risk Management
                  - Drug Shortages & Recalls
                  Topic 3: Person-Centered Assessment & Care Planning40%- Therapeutic Appropriateness
                  • 1. Special Populations
                    • 2. Evidence-Based Guidelines
                      • 3. Indication & Dosing Regimens
                        - Patient Monitoring & Follow-Up
                        • 1. Therapeutic Outcomes Assessment
                          • 2. Treatment Adjustment
                            • 3. Clinical & Laboratory Evaluation
                              Topic 4: Professional Practice5%- Immunization & Wellness Services
                              - Patient Counseling & Education
                              - Public Health & Regulatory Compliance
                              Topic 5: Medication Use Process25%- Order Verification & Preparation
                              • 1. Prescription Review & Accuracy
                                • 2. Dosage Form & Route Selection
                                  • 3. Labeling & Dispensing Standards
                                    - Medication Safety
                                    • 1. Drug Interactions & Contraindications
                                      • 2. Adverse Effects & Risk Management
                                        • 3. Error Prevention Strategies

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